top of page

A Functional Nutrition Approach to Treating Cognitive Decline: The Dale Bredesen Protocol


Cognitive decline, a common consequence of aging, can significantly impact the quality of life for individuals and their loved ones. However, the groundbreaking research and work of Dr. Dale Bredesen, a renowned neurologist and expert in the field of Alzheimer's disease, have given hope to many suffering from cognitive impairments. At Buffalo Nutrition & Dietetics, PLLC, our team of dedicated Registered Dietitians specializes in functional medicine nutrition and is proud to offer the transformative Dale Bredesen Protocol as a powerful tool in treating cognitive decline. In this blog post, we will delve into the fundamentals of this protocol and explore how functional medicine nutrition plays a pivotal role in the treatment of cognitive decline.

Understanding the Bredesen Protocol

Dr. Dale Bredesen's protocol is a comprehensive, personalized therapeutic approach designed to address the multi-faceted nature of cognitive decline. It acknowledges that Alzheimer's disease and other forms of cognitive impairment are not caused by a single factor but rather result from the convergence of various biological processes. The Bredesen Protocol targets three fundamental areas to combat cognitive decline:

  1. Inflammation: Chronic inflammation in the brain is believed to play a critical role in the development of neurodegenerative diseases. The protocol focuses on identifying and mitigating sources of inflammation, including infections, food sensitivities, and environmental toxins.

  2. Insulin Resistance: Insulin resistance affects brain health and can impair glucose utilization, contributing to cognitive decline. Addressing insulin resistance through dietary and lifestyle modifications is an integral part of the protocol.

  3. Nutrient Imbalances: Nutrient deficiencies can impact brain function and exacerbate cognitive decline. The protocol aims to optimize nutrient intake through personalized dietary plans and targeted supplementation.

Functional Nutrition in the Bredesen Protocol

As functional medicine dietitians, we understand that nutrition plays a vital role in promoting brain health and preventing cognitive decline. Our team of expert RDNs will guide you through the following key components of the functional nutrition approach in the protocol:

  1. Ketogenic Diet: With our guidance, you will embrace a modified ketogenic diet that encourages the consumption of healthy fats and restricts carbohydrates. This dietary approach helps improve brain metabolism and energy production, particularly in individuals with insulin resistance. We are able to modify this for coinciding medical conditions in those who are unable to follow it exactly.

  2. Nutrient-Dense Foods: We emphasize the importance of nutrient-dense foods, rich in antioxidants, vitamins, and minerals, to support brain health. Colorful fruits and vegetables, fatty fish, nuts, and seeds will be an integral part of your personalized nutrition plan.

  3. Intermittent Fasting: Intermittent fasting, known for promoting brain function and reducing inflammation, may be incorporated into your plan to optimize brain health.

  4. Gut Health: We recognize the significance of the gut-brain connection. Our expert Registered Dietitians will guide you in implementing gut-supportive measures, such as probiotics and prebiotics, to reduce inflammation and enhance nutrient absorption.

  5. Targeted Supplementation: Based on your specific needs and lab test results, we will recommend personalized supplements to correct nutrient imbalances and support cognitive function.

  6. Stress Reduction: Chronic stress can negatively impact brain health. Our team will introduce stress reduction techniques, such as meditation, yoga, and mindfulness, to complement your personalized nutrition plan.

Personalization and Expert Guidance

One of the strengths of the Bredesen Protocol is its personalized nature. As functional medicine dietitians, we understand that every individual's cognitive decline may stem from different root causes, and a one-size-fits-all approach is not suitable. Through comprehensive testing and analysis, our RDNs tailor the protocol recommendations to the specific needs of each patient.


The Bredesen Protocol, represents a groundbreaking advancement in the field of functional nutrition and cognitive decline treatment. By addressing the underlying factors contributing to cognitive impairment, this approach provides hope for individuals seeking to improve their brain health and reverse the effects of cognitive decline. Through a combination of dietary modifications, lifestyle changes, and targeted supplementation, our competent Registered Dietitians will guide you on a journey towards better brain health and enhanced overall well-being.

As part of our commitment to comprehensive care, we collaborate with Dent Neurologic Institutes's Functional Medicine and Brain-Gut Clinics. This partnership brings together the expertise of experienced specialists in neurology, functional medicine, and brain-gut health to offer you a multidisciplinary approach to your cognitive well-being. Together, we strive to provide you with the highest level of care and support on your path to better brain health.

Remember, the Bredesen Protocol should always be administered under the guidance of qualified healthcare professionals with training and expertise in functional medicine and nutrition. If you or a loved one are experiencing cognitive decline, consider exploring the personalized and expert care offered by Buffalo Nutrition & Dietetics, PLLC as a potential path to a brighter future.

105 views0 comments

Recent Posts

See All


bottom of page